Opioid but not nonopioid stress-induced analgesia is enhanced following prenatal exposure to ethanol
نویسندگان
چکیده
منابع مشابه
Amniotic fluid ingestion enhances opioid-mediated but not nonopioid-mediated analgesia.
Ingestion of amniotic fluid or placenta by rats has been shown to enhance several types of opioid-mediated analgesia: that induced by morphine, footshock, vaginal/cervical stimulation, and late pregnancy. This enhancement has also been blocked by administration of opioid antagonists. The present study was designed to examine further the specificity of the enhancement effect for opioid-mediated ...
متن کاملHippocampal cell proliferation is reduced following prenatal ethanol exposure but can be rescued with voluntary exercise.
The ingestion of ethanol during pregnancy has a number of deleterious consequences for the unborn offspring, producing structural and functional deficits that affect the brain and many other organs into adulthood. The hippocampus is a brain area that is particularly sensitive to ethanol's adverse effects. In a previous study we showed that voluntary exercise can ameliorate deficits in long-term...
متن کاملEffect of cold acclimation and repeated swimming on opioid and nonopioid swim stress-induced analgesia in selectively bred mice.
Swiss-Webster mice selectively bred for high swim stress-induced analgesia (SSIA) were exposed to continuous ambient cold (5 degrees C) for 6 weeks or to daily 3-min swims for 14 consecutive days either in 20 or 32 degrees C water. Thereafter, mice subjected to the particular procedure were injected intraperitoneally with 10 mg/kg of naltrexone HCl and were tested for modification of the opioid...
متن کاملPain sensitivity of fishes and analgesia induced by opioid and nonopioid agents
Experiments were performed on carp Cyprinus carpio, rainbow trout Oncorhynchus mykiss, cod Gadus morhua and sturgeon Acipenser ruthenus. An originally designed optico-mechanical system was used to record the response to painful electrical stimulation. before and after administration of analgetic agents. Drugs used were mu agonists tramadol, dermorphine and beta-casomorphine, kappa agonist U-504...
متن کاملNonopioid analgesia improves outcomes.
In Reply:—We thank Chelly et al. for their interest in our case report that described major ambulatory surgery with continuous regional anesthesia and a disposable infusion pump. Although we appreciate their comments, we believe the use of continuous local anesthetic infusions at home is an investigational area of pain control. As a result, despite their institutional bias, many of the issues t...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Psychopharmacology
سال: 1985
ISSN: 0033-3158,1432-2072
DOI: 10.1007/bf00427329